Capabilities

Oyagen Capabilities

Technologies for Contracting Out

  1. Biochemistry, Biophysical, Cell Biology and Molecular Methods
    Assay development
    Cell transfection (transient and stable cell lines)
    Crystallography
    Electrophoretic mobility gel shift
    Gene cloning and sequence analysis
    Enzyme assay development for HTS
    Flow cytometry
    FRET
    Florescent cell imaging (probe localization and intracellular trafficking)
    High throughput/high content assay and critical path design and development
    In silico drug-target interaction modeling
    Isothermal Calorimetry
    Macromolecular structural modeling
    PAGE (1D, 2D) western blotting
    PCR, multiplex PCR, real time PCR, RT-PCR
    Protein and RNA expression
    Size exclusion chromatography and ion exchange chromatography
    Surface plasmon resonance
    Thermal shift assay
    Ultracentrifugation and sedimentation analysis

  2. High Through-put Facilities
    Chemical Libraries 25,000 diversity set library and assorted smaller libraries

  3. Optics/Mictroscopy/Spectroscopy
    LKB biochem Ultrospec II 4050 UV/visible Spectrophotometer
    Vistavision VWR Upright Compound Microscope
    Olympus IX81 and Hamamatsu Orac-C8484-05G02 camera
    UVP BioSpectrum Imaging System

  4. Mammalian Tissue Culture
    Two Forma seven foot BioSafety cabinets
    Thermo Scientific Heracell 150i CO2 incubator
    Forma Scientific CO2 water jacketed incubator Series II

  5. Microogranism-Based Assays
    Bacterial Based Assays

  6. Centrifugation
  7. Molecular Biology